Dear all,
I found this an interesting read:
Cooley, N.P., Wright, E.S. Many purported pseudogenes in bacterial genomes are bona fide genes. BMC Genomics 25, 365 (2024). https://doi.org/10.1186/s12864-024-10137-0https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-024-10137-0
It's actually more about assembly quality (and its factors) than about pseudogenes as such. I like their idea that pseudogene count could be used as an indicator of genome quality. Makes sense if you consider that it is biologically improbable to find a pseudogene where the closest reference has a functional gene.
Marco
Dear all,
This took a while to get right, but finally we are up and running!
This mailing list was set up for the SeqAfrica Bioinformatics Community
of Practice, but is open to all bioinformaticians with an interest in
microbial (AMR) genomics.
The bioinfo-list is publicly archived at [1] (where you are probably
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Kind regards,
Marco
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